La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Vanessa Richardson - So wonderful!

    First, let me tell you what I do not like about this serum. It needs to be a pump instead of an eye dropper. I don't care how careful you are but pulling the eye dropper in and out gets messy and you waste serum getting on all sides when you screw it back on. Even though I do not like that part I still gave it a five.

  • Tina S. - The lid seals tight and it's easy to grip

    This cup is fabulous! I purchased a Starbucks coffee, which I drink every morning and dumped it into this cup. After one hour it was still hot-hot. After two hours it was still very warm. After three hours it was luke warm but not near cold. Coffee wouldn't typically last me that long but I was purposefully testing it out. The lid seals tight and it's easy to grip... I do wish it was a tad bit smaller and had a slide close on top so I could double it as a soup thermos for my kids who take lunches to school... I will be looking for them to come out with that next ☺️