La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

A Privately Held Medical Device Company and Developers of the NeuroStar TMS Therapy System® - Neuronetics, Inc. is a privately held medical device company focused on developing non-invasive therapies for psychiatric and neurological disorders using MRI

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  • RachelR - Excellent Authors!

    The spiritual teachers of our time! Instead of being told to do this and that the gentle reminders of make a choice for yourself are highlighted throughout the book. This is the book that launched me out of "spiritualized ego" !! I highly recommend it and all of their works. Make a choice!

  • Kelly Ray - Great Deal-buy early & save on the pre-sale price

    I love this book! We are very frugal & it adds to the places that we can eat t for a bargain price. Had issues with the Long Horn casino on Boulder Hwy- they don't know how to cook a steak med/well or med/rare-they were so raw that they would have been called bleu (I spelled it correctly) in other words rarer than rare! I sent it back 2 times & it came back the same both times, then the cook came out & gave me attitude! The restaurant mgr wasn't there & the casino mgr backed him. The server had problems with the cook that night. While we were there 3 other tables sent back their steaks as well! But that wasn't the books fault. We live in a suburb of vegas so we really enjoy this book. I will buy it every year for the rest of my life!!! If you use it once or twice it pays for itself.