La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

Home - Northern Virginia Pediatric Associates, P.C. is a medical practice whose primary purpose is to care for the physical and mental health of children from birth until age 21 and to provide support and guidance for parents and family members.

Country: 108.167.175.248, North America, US

City: -95.4739 Texas, United States

  • Richard Neal - Hallmark Can Do Better, Surely?

    I actually prefer the older version because taking three hours to install was very frustrating, especially when told it may take a few minutes and it took 90 minutes and it still didn't work and I had to try again, it kept telling me it was loading, but after 30 minutes I gave up, but when I did an update it seemed to work, but c'mon Hallmark you can do better!!

  • LASO - he was disappointed as he did not feel the beer tasted any ...

    Bought for my husband at Father's Day ... he was disappointed as he did not feel the beer tasted any different, and not like draft. Can use it to keep beer cool though.