La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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    I recently switched over to seachem water conditioner from the API stresscoat as I noticed it helps to neutralize toxic ammonia. The price is a good value and it only takes a small amount 5ml/50g. The product arrived quickly and as pictured. Seems to be working out fine as I havent had any disruptions in my tank. I had to dock a star because the cap on the bottle leaks. Whenever I shake the bottle, liquid comes out on my hand which is very annoying as this product does have a smell. However this is a good product overall.