La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
Portal o Saber da Cerveja - MWTrommer é uma empresa do segmento de bebidas com ênfase em cervejas. Presta assessoria em todas as áreas na produção e comercialização além de oferecer cursos e palestras dedicadas ao assunto.
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Reasonably priced . working good so far. Bought it for my 16 year old son who is always on the go and he loves it!!
I am a relearner of geometry, having been years since I have been in high school. A lot of new stuff is in this text than what I remember. I love the "Key Concepts" which identify the main idea I have to learn. The theorems and postulates are well written and thoroughly explained. There are several ways to review concepts. I do wish the answers to the "Guided Practice" problems, which help to learn from the examples, were in the back of the book. As a self-study learner, I find the text easy to understand and would recommend this edition.