La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Dyann - Hate it. Big

    Hate it.Big, Bulky, hard to store, used it twice and food was not good. Probably good for someone else, just not for me.

  • Kay Park - Doesn't Make Any Sense...What a Waste

    This is one of the worse books I've ever had the misfortune to read. I will admit right now I stopped reading it because it made noooo sense. I tried. I really tried to muddle through but I couldn't. Perhaps 18 year olds are that stupid and I can't relate but you're drugged and raped and so you're ashamed to admit that so instead you say you voluntarily filmed a porn film with two guys. Really????? And you continue to insist on that lie? And the supposedly mature 35 year old man is just as weak and spineless too. What a total waste.

  • Naomi D - Isa believer

    I started using Isa products in July 2012 (shakes and a daily cleanse). Love the shakes. So creamy; just like a milkshake. Just finished my first 9 day deep cleanse and feel amazing! I lost 8 lbs and 11 inches in 9 days for a total of 25 lbs and nearly 30 inches since July (about 9 months). I would be somewhat weary of older reviews saying they didn't like the taste of the products. They change the formulas periodically so they may be completely different now than in 2009! I find the that cleanse drink tasts like fruit juice - i drink it over ice and it goes down just fine.

  • Grazi - it's a fresh smell like if you just got out of the shower

    My husband loves this cologne. It's a not too strong, it's a fresh smell like if you just got out of the shower. I buy it to my husband every time he's running out of it, the quality for that price is what keeps me buying it over and over.

  • L Black - Social Security Demystified

    I use this book in our Retirement Planning Seminars. This is a fantastic resource on all things related to the Social Security System and how you can benefit from it. Andy Landis is both knowledgable and concise. A must own.

  • kristi desmidt - Doesn't work

    I do not recommend. I tried it, and it does nothing. I was still hungry, and did not lose any weight.