La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

HOMEPAGE - PTCRIN - Universidade Nova de Lisboa - PtCRIN PUBLICATION:Investigator-initiated clinical trials conducted by the Portuguese Clinical Research Infrastructure Network (PtCRIN) Author(s): C. Madeira, A

  • http://www.ptcrin.pt/p41-area-reservada-en ÁREA RESERVADA - PTCRIN - Universidade Nova de Lisboa - PtCRIN - Portuguese Clinical Research Infrastructure is an infrastructure with the mission of promoting national and international cooperation in clinical resea
  • http://www.ptcrin.pt/p18-vision-mission-objectives-en Vision, Mission & Objectives - PTCRIN - Universidade Nova de Lisboa - VISION We promote innovation, competitiveness, and quality in investigator initiated clinical trials (IICT) in Portugal.MISSION PtCRIN is an infrastructure dedi
  • http://www.ptcrin.pt/p39-organization-en Organization - PTCRIN - Universidade Nova de Lisboa - PtCRIN is a Portuguese Clinical Research Infrastructure Network initiated under the scope of the European Project ECRIN-IA: European Clinical Research Infrastru
  • http://www.ptcrin.pt/p57-contacts-en Contacts - PTCRIN - Universidade Nova de Lisboa - PtCRIN MANAGEMENT OFFICE NOVA Medical School | Faculdade de Ciências Médicas, UNLEdifício CEDOC I, Rua do Instituto Bacteriológico, nº 5, 2º1150-190 Lisbo
  • http://www.ptcrin.pt/p37-advice-and-consultancy-en Advice and consultancy - PTCRIN - Universidade Nova de Lisboa - PtCRIN can advise Investigator Initiated Clinical Trials (IICT) in Portugal and provide advise on the following: National and internacional regulatory and ethic
  • http://www.ptcrin.pt/p21-training-en Training - PTCRIN - Universidade Nova de Lisboa - The success of a clinical research is also dependent on the proficiencies of the specialists involved. Therefore, we encourage all the health care professionals
  • http://www.ptcrin.pt/p22-quality-en Quality - PTCRIN - Universidade Nova de Lisboa - PtCRIN aims to implement a QUALITY MANAGEMENT SYSTEM (QMS) for clinical research and ensure that all requirements for the development of a clinical research pro
  • http://www.ptcrin.pt/p61-regulatory-en Regulatory - PTCRIN - Universidade Nova de Lisboa - NATIONAL This database contains information about Portuguese Regulation on Clinical Trial’s. It also includes contact addresses of national authorities, natio
  • http://www.ptcrin.pt/p60-clinical-trial-road-map-en Clinical Trial Road Map - PTCRIN - Universidade Nova de Lisboa - The portuguese version of the Clinical Trial Toolkit is an interactive route map that will guide you through the main procedures for the design and implementati
  • http://www.ptcrin.pt/p62-partnership-en Partnership - PTCRIN - Universidade Nova de Lisboa - NATIONAL CLINICAL RESEARCH NETWORKS Biobanco.pt Portuguese Platform of Biolmage Translational and Clinical Research Infrastructures Specialisation Platform Port
  • http://www.ptcrin.pt/p65-national-en National - PTCRIN - Universidade Nova de Lisboa - Gabinete de Promoção do Programa Quadro de I&D& ANI - Agência de Inovação FINANCIAMENTO PARA A SAÚDE NO HORIZONTE 2020 O Desafio Societal 1 do Horizonte 2
  • http://www.ptcrin.pt/p67-patients-and-public-en Patients and Public - PTCRIN - Universidade Nova de Lisboa - WHAT IS A CLINICAL TRIAL ? A clinical trial is a research study conducted in humans with the purpose of answering specific questions about new medicines or new
  • http://www.ptcrin.pt/p68-investigators-en Investigators - PTCRIN - Universidade Nova de Lisboa - WHAT IS A SPONSOR INVESTIGATOR? An individual (not a corporation) who both initiates (plans and designs) and conducts a research project in an health-care insti
  • http://www.ptcrin.pt/p70-ask-about-en Ask About - PTCRIN - Universidade Nova de Lisboa - We would welcome your feedback and suggestions on how we can improve.Please help us to keep this website and tools up-to-date by reporting any out-of-date conte

    Country: 188.93.225.5, Europe, PT

    City: -9.1394 , Portugal

  • RedErin - Dries my skin and looks cakey

    This didn't work for me at all. It's too thick, much more like a regular foundation. It doesn't blend well. And it dries out my skin. After I put this on my skin would start to flake. This was a waste of money.

  • Lolly - Snot sucking so easy!!

    I'll preface this review by saying I have two graco aspirator and nose Frieda. The baby vac is most impressive of all. I'm happy to have found it now but honestly bummed I didn't get it sooner. If your serious about getting the snot and phlem out of anyone's nose this is your device. I don't recommend the graco, the Frieda works but gets you sick in the process (yes bacteria passes through the snot filter)

  • Madelyn Carlton - So disappointed in this product

    So disappointed in this product. Please don't waste your time and money with this tablet. Amazon, however, was so great about the return of the product. It only took maybe five minutes to get a return authorization. Thank you Amazon for being so wonderful!

  • DayTrader - Customer support, please

    I can't figure out how to use it. Maybe they need to make pens specifically for lesbians. But I will admit they're sexy as hell, all pressed up against each other in the bag like that...

  • Heather W. - I LOVE this calendar

    I LOVE this calendar. Great space to track and plan my days. The pictures are fun to color and the quotes with each picture is meaningful.