La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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    I was really excited to finally use WEN but I used it and it made my hair greasy the fist time. I used it again my hair wasnnt greasy the second time but not soft at all. I will stick with my Suave Professionals.

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    This is the sweetest little book that your little one is sure to love. It is perfect for Dad to read to his little boy. The illustrations were very nicely done. I would recommend this book for little boys everywhere!

  • Neur0n - Regret ever purchasing this game.

    I bought this when it first came out. I been waiting for this game for years. The game was in development for an extremely long time, and the hype for this game was insane. The first few trailers looked awesome, except for the fact they were all movie scenes and not a single game play. I'm extremely disappointed that it took Blizzard all these years to produce this. Only reason they sold as much as they did was because of the hype.