La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Darin Russell Wight - It is great remove the hair only on rough skins instead of sensitive skins!

    It is good for everything to remove your hair except the genitals part. It is really hurt on the sensitive skins. Also, your face! Be aware! It is powerful formula line acid!

  • DPannell - LOVE this Shampoo!

    I purchased this shampoo for my petite goldendoodle and hairless chinese crested dogs. This shampoo is great! It cleans their coat and skin thoroughly, has excellent and beneficial ingredient properties, is soothing to their skin (no scratching, digging, rolling in misery or discomfort), and smells terrific! Plus, it leaves them smelling fresh and clean at least two weeks! I have finally found a shampoo which works great!

  • D. Steinley - Vault

    Looked at these before, but always thought they were rather pricey. However, they are quite well made. Design allows for the supplied hitch pins to be secured on the inside of the locking compartment, so no one can just disconnect this vault from your receiver hitch. All seams where dirt and moisture could seep in are covered by foam rubber gaskets, so I am hopeful they work as designed! Heavy duty, and I have had to use it once already to let myself in! All in all, although pricey, worth the buy and the peace of mind!