La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.
The Kids Are All Right - Parenting teenagers in Australia - The Kids Are All Right supports parents of teenagers with information, resources and an online community to share parenting advice.
Country: 103.37.8.133, Oceania, AU
City: 143.2104 , Australia
I love this stroller. Would give it more stars if I could. Very easy to maneuver, with a short turning radius, great in stores. Eexcellent hood which really protects the baby from too much sun while being able to view her thru the mesh window. Excellent handle and the bar in front of your feet is curved so you dont kick it while walking. Folds and unfolds very easily. All in all very well designed and convenient. Only quibble would be having to buy the extra child's tray although it is quite nicely designed. The drink holder for the adult is less well designed and needs to be removed in order to fold the stroller. A disappointment given how well designed the stroller is.
Great cycling computer... Nice compact size with still very readable screens... Ties in easily to speed/cadence & heart rate monitors, Bluetooths easily to my S7Edge, automatically uploads, great stats for analysis, very good notification features...