La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • J. Welsh - I liked it so much I bought TWO!

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    Ok, so actually I did not like the bed. Had a lot of back and other pain that didn't go away. But I talked with others who used the mattress and loved it, so I think it's probably great for some people and not others.

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    I have used this program for years for a small business. It is awesome! Does everything I need it to do and you can't beat the price!

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    Love this knife set, bought it for family. I admit I have a two man set, have had it for over 20 years and still going strong. Hardly ever needs sharpening. Those sets are now $199. However for the price this set is great, very sharp. Good weight, fits your grip. Will it last 20 years, dont know.

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