La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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Country: 54.93.120.190, Europe, DE

City: 8.6833 Hesse, Germany

  • Jeffrey D. Hauck - Libman Wonder Mop

    Consumer Reports rated the Libman Wonder Mop a best buy. I took a chance and ordered for a relative, who hate the sponge type and more expensive proprietary products in the market. They were so thrilled with it, I ended up buying for my household. It is definitely superior to the aforementioned products. Recommend to everyone.

  • Amazon Customer - ... helmets for years and thought this would be a good replacement. I like everything about the helmet except ...

    I have used Giro helmets for years and thought this would be a good replacement. I like everything about the helmet except the strap. My old Giro had a thicker strap with rounded edges that was comfortable on my face. The straps on this one are very thin and tend to dig in my chin when I look down.

  • Danielle - Love them. Easy to use

    I bought two of these for my boyfriend and I to try out. Love them. Easy to use, and everywhere I get a compliment on it. So easy to use, the night before i put in whatever fruit I'm in the mood for, place it in my refrigerator, and its ready to go the next day. Through out the day i refill it with the sam fruit, and discard the fruit at the end of the day to make a new one. The best part is it is super easy to clean. No hassle at all.

  • J. White - Poor UI

    1. The UI is really poor, I was shocked when I started using it that any company could survive this long with such a poor UI. Many controls are homemade or hacks of the Win95 (1995!!) controls, they have unusal behaviors and are very annoying:

  • Suzy - Great little device!

    Great little device! I like to do my nails just before I go to bed so that I can lay my hands on top of the sheets and let them dry as I go to sleep. The problem is, I would try to hold the bottle between my raised knees, and it would slip and slide around. With Tweexy, I can do my nails anywhere, without having to squeeze the bottle between my knees, or needing to have a flat surface to keep it on. My tween daughter loves it, too!