La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Nancy - Simple, Easy, and wayyy Cheaper! Way to go Norton!

    Based on other reviews, I had alot of doubts if whether or not I would get the downloadable software version of Norton. First of all, It was alot of cheaper than in Stores! (Which would be around like $40!) and i got it for $15! I had some doubts about it, just because everyone kept saying that it didn't download, or it wasn't the right version and all. But at last I gave in, and bought it anyways. Well it turned out to be simple! Downloaded it, installed it, and boom, and worked right away!! No problems at all. So for sure next time when my software expires, im doing this again.! Just make sure when you install it, you update the pin code that way you'll get it. But ovarall it was awesome!:)

  • Damien Klassen - Proceeding with caution

    We bought this book and tested its recommendations on my 3 year old with a severe development delay.