La doxycycline, membre de la famille des tétracyclines, agit par inhibition de la fixation de l’ARNt sur la sous-unité 30S du ribosome, empêchant l’élongation de la chaîne peptidique. Elle se caractérise par un spectre très large incluant bactéries atypiques, rickettsies, chlamydiae et spirochètes. Sa biodisponibilité digestive est excellente, mais elle est diminuée en cas d’ingestion simultanée de sels de calcium, fer ou magnésium. La doxycycline diffuse bien dans les tissus et possède une demi-vie longue, permettant des administrations biquotidiennes. Elle est éliminée principalement par voie biliaire. Les précautions concernent le risque de photosensibilisation, d’hyperpigmentation dentaire et de troubles digestifs. Dans les recommandations cliniques, la mention doxycycline sans ordonnance est souvent accompagnée de rappels sur la nécessité d’éviter son usage chez l’enfant et la femme enceinte, ainsi que sur la surveillance des traitements prolongés.

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  • Casey Holley - Supply dried up. Not happy.

    Not impressed at all. Took this for two days and my supply dried up. Maybe this works for some women, but I had to stop breastfeeding after taking this. I usually take a different lactation blend, but someone said this one was better. I honestly wish that I had just stuck to what I KNEW worked. Very sad as my son is a preemie and I wanted to breastfeed for at least 6 months to a year.

  • Belaleah - Disappointing

    I bought this specifically to clean a few small glass vases which had built up a film from being used over the years. I tried repeatedly to clean them with the CLR. They look a little better than they did but certainly nothing like the nice clear glass I had hoped for.